Research Article

IDH1/IDH2 but Not TP53 Mutations Predict Prognosis in Bulgarian Glioblastoma Patients

Table 2

Clinical features of the patients with mutations in IDH1/IDH2 and TP53 genes.

Clinical characteristicsN ( )IDH1/IDH2 mutated ( )TP53 mutated ( )

Gender
 Male538 (15.1%)20 (37.7%)
 Female536 (11.3%)17 (32.1%)
Age
 <56 years old5112 (23.5%)22 (43.1%)
 ≥56 years old 552 (0.36%)15 (27.3%)
Karnofsky Scalea
 KPS ≤70563 (0.5%)15 (26.8%)
 KPS >704510 (22.2%)21 (46.6%)
Resectiona
 Subtotal or partial5410 (18.5%)21 (38.8%)
 Total504 (0.8%)16 (32%)
Glioblastoma type
 Primary9310 (10.7%)29 (31.2%)
 Secondary134 (30.7%)8 (61.5%)
Overall survivala (months)
 Median7.730.99.1

Missing data for several patients.
N: number of patients.