A Comparative Performance Analysis of Total PSA, Percentage Free PSA, PSA Velocity, and PSA Density versus the Detection of Primary Circulating Prostate Cells in Predicting Initial Prostate Biopsy Findings in Chilean Men

Table 1

Clinical variables in men with positive and negative initial biopsy.

	Positive biopsy	Negative biopsy	𝑃
Age	65.5 ± 9.8	64.8 ± 8.4	𝑃 = 0.52
PSA ng/mL	6.10 (IQR 4.67–9.6)	5.58 (IQR 4.45–7.64)	𝑃 = 0.09
% free PSA	11% (IQR 9–15%)	17% (IQR 13–23)	𝑃 ≤ 0.001
PSA velocity ng/mL/yr	0.85 (IQR 0.59–2.05)	0.58 (IQR 0.12–1.15)	𝑃 = 0.006
Prostate volume	44 ± 18	57 ± 24	𝑃 = 0.001
PSA density	0.17 (IQR 0.11–0.25)	0.11 (IQR 0.08–0.17)	𝑃 = 0.006
CPC (+)	100/113	22/190	𝑃 < 0.0001