Nuclear Distribution of RNA Polymerase II and mRNA Processing Machinery in Early Mammalian Embryos
Figure 2
The distribution of SR protein SC35 (a), (c), hyperphosphorylated RNA polymerase II (PolII) (b), (d) in control (a), (b), and arrested in vitro 2-cell mouse embryos (c), (d). Note the large SC35 speckles enriched in hyperphosphorylated RNA polymerase II in the nucleus of blocked embryo. Scale bar is 5 μm, according to [26], reprinted from Tissue and Cell; Bogolyubova. Transcriptional activity of nuclei in 2-cell blocked mouse embryos 2011; 43: 262-265 [26], with permission from Elsevier.
