Clinical Study
Microbleeds in Late-Life Depression: Comparison of Early- and Late-Onset Depression
Table 1
Demographic, neuropsychosocial, and radiological characteristics of all subjects.
| | Control () | EOD () | (versus control) | POD () | (versus control) | LOD () | (versus control) |
| Age, years | | | 0.669 | | 0.422 | | 0.236 | Female | 41 (48.2%) | 37 (64.9%) | 0.050 | 35 (64.8%) | 0.056 | 53 (63.1%) | 0.052 | Education, years | | | 0.956 | | 0.238 | | 0.645 | Hypertension | 52 (61.2%) | 37 (64.9%) | 0.652 | 33 (61.1%) | 0.994 | 59 (70.2%) | 0.215 | Diabetes | 24 (28.2%) | 12 (21.1%) | 0.335 | 16 (29.6%) | 0.860 | 29 (34.5%) | 0.378 | MMSE | | | 0.522 | | 0.038 | | 0.002 | LSNS | | | 0.000 | | 0.001 | | 0.050 | SLE | | | 0.000 | | 0.000 | | 0.511 | GDS | | | 0.000 | | 0.000 | | 0.000 | Grade of PWMH | | | 0.214 | | 0.038 | | 0.000 | Grade of DWMH | | | 0.441 | | 0.182 | | 0.000 | Prevalence of SBI | 28 (32.9%) | 17 (29.8%) | 0.696 | 25 (46.3%) | 0.114 | 47 (56.0%) | 0.003 | Prevalence of microbleeds in | | | | | | | | Any region | 20 (23.5%) | 13 (22.8%) | 0.920 | 15 (27.8%) | 0.574 | 35 (41.7%) | 0.012 | Left hemisphere | 10 (11.8%) | 7 (12.3%) | 0.926 | 12 (22.2%) | 0.100 | 28 (33.3%) | 0.001 | Right hemisphere | 14 (16.5%) | 10 (17.5%) | 0.721 | 8 (14.8%) | 0.794 | 20 (23.8) | 0.234 | Infratentorial | 9 (10.6%) | 5 (8.8%) | 0.722 | 7 (13.0%) | 0.669 | 13 (15.5%) | 0.345 | Lobar | 10 (11.8%) | 8 (14.0%) | 0.690 | 11 (20.4%) | 0.167 | 27 (32.1%) | 0.001 | Deep | 14 (16.5%) | 11 (19.3%) | 0.665 | 9 (16.7%) | 0.976 | 22 (26.2%) | 0.123 |
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EOD: early-onset depression; POD: presenile-onset depression; LOD: late-onset depression; MMSE: minimental state examination; LSNS: Lubben Social Network Scale; SLE: Scale of Life Events; GDS: Geriatric Depression Scale; PWMH: periventricular white matter hyperintensities; DWMH: deep white matter hyperintensities; SBI: silent brain infarction.
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