Pomegranate Fruit as a Rich Source of Biologically Active Compounds

Table 2

Effect of E2, PME, and tamoxifen on chosen markers of bone metabolism of ovariectomized mice. Serum calcium, phosphorus, and Alkaline Phosphatase (ALP) levels of sham control (SS Con) and Ovx mice exposed to 0.1% ethanol (vehicle control), E2 (1 mg/kg bwt), PME (50, 100 mg/kg bwt), and tamoxifen (TAM, 10 mg/kg bwt) for 7 days (bwt = body weight). Data are expressed as mean ± SE (𝑛=5).

	Sham control	OVX control	E2; (1 mg/kg bwt)	PME; (50 mg/kg bwt)	PME; (100 mg/kg bwt)	TAM; (10 mg/kg bwt)
Calcium (mg/dL)	9.46 ± 0.313	10.94 ± 1.18	8.188 ± 0.7040^a	8.5 ± 0.707	9.09 ± 0.194	9.908 ± 0.165
Phosphorus (mg/dL)	7.43 ± 0.63	8.818 ± 0.698	8.026 ± 1.066	7.516 ± 1.731	8.78±1.980	8.146 ± 0.0680
ALP (U/L)	140.6 ± 11.28	181.8 ± 34.07^a	115.2 ± 23.61^b	130.4 ± 12.77	120 ± 9.02^b	134.6 ± 17.54^b

^a𝑃<0.05 versus sham control, ^b𝑃<0.05 versus ovx control.