MiR-15b Targets Cyclin D1 to Regulate Proliferation and Apoptosis in Glioma Cells

Figure 1

(a) MiR-15b expression in glioma tissues and normal brain specimens. The relative levels of miR-15b were measured by real-time PCR assay. (b, c) MiR-15b expression increased about 5.02-fold and 3.98-fold, at 48 h after transfection of miR-15b mimics in U87 and LN229 cells, respectively. Total RNA was extracted using Trizol reagent. The relative expression of miR-15b was calculated by using a 2⁻ΔΔCt method. The data are presented as the mean ± SD. ^∗∗𝑃<0.05 compared to the control.

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