MiR-15b Targets Cyclin D1 to Regulate Proliferation and Apoptosis in Glioma Cells

Figure 4

MiR-15b suppresses the growth of glioma cells. (a) MTT assay reveals a significantly inhibitory effect of miR-15b mimics treated cell (Student’s 𝑡-test). (b) Overexpression of miR-15b results in the cell cycle arrest at G0/G1 phases in glioma cells. (c) MiR-15b induced apoptosis in both U87 and L229 glioma cells (Student’s 𝑡-test). The data are presented as the mean ± SD. ^∗∗𝑃<0.05 compared to the control.

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