Research Article

MiR-15b Targets Cyclin D1 to Regulate Proliferation and Apoptosis in Glioma Cells

Figure 5

Cyclin D1 plays a crucial role in the suppressive proliferative process of miR-15b in glioma cells. (a) Western bolt analysis displays that ectopic of Cyclin D1 abrogates the miR-15b-mediated Cyclin D1 expression partly. (b) Ectopic expression of Cyclin D1 counteracts the G1 arrest induced by miR-15b in glioma cells. The representative results out of three times of experiments were shown here.
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(a)
687826.fig.005b
(b)