Research Article
Formulation Optimization of Erythromycin Solid Lipid Nanocarrier Using Response Surface Methodology
Table 1
Independent variables along with their coded level, actual level, and respective responses values of different batches of ERY-SLNs.
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Form. code | Coded level | Actual level | Responses | | | | | Mean particle size (nm) | Polydispersity index (PDI) | Zeta Potential (mV) | EE (%) | DL (%) |
| SLN 1 | −1 | −1 | 15 | 01 : 02 | | | | | | SLN 2 | −1 | 0 | 15 | 01 : 01 | | | | | | SLN 3 | −1 | 1 | 15 | 02 : 01 | | | | | | SLN 4 | 0 | −1 | 20 | 01 : 02 | | | | | | SLN 5 | 0 | 0 | 20 | 01 : 01 | | | | | | SLN 6 | 0 | 1 | 20 | 02 : 01 | | | | | | SLN 7 | 1 | −1 | 25 | 01 : 02 | | | | | | SLN 8 | 1 | 0 | 25 | 01 : 01 | | | | | | SLN 9 | 1 | 1 | 25 | 02 : 01 | | | | | |
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