Newborn Screening for Sickle Cell Disease: Technical and Legal Aspects of a German Pilot Study with 38,220 Participants

Table 2

High interrun precision of HPLC retention times of retention time markers.

Hemoglobin	Retention times of RTM mean (range) [min]	CV [%]	Manufacturer’s specifications mean (range) [min]
F	0.494 (0.471–0.510)	1.5	0.530 (0.470–0.590)
A	0.792 (0.770–0.804)	0.9	0.800 (0.730–0.870)
E/A2	0.954 (0.919–0.970)	1.0	0.970 (0.930–1.010)
D	1.042 (1.005–1.072)	1.1	1.060 (1.010–1.110)
S	1.158 (1.116–1.183)	1.2	1.190 (1.130–1.250)
C	1.663 (1.634–1.684)	0.6	1.680 (1.610–1.750)