Cationic Polyene Phospholipids as DNA Carriers for Ocular Gene Therapy
Figure 4
Gel retardation assays with lipoplexes C20-18 (a), C20-20 and C30-20 (b), DC-Chol (c), and EPC (d) with DOPE and Chol as colipids. Molar charge ratios N/P used were 0.5 : 1, 1 : 1, and 1.5 : 1. Retention of DNA increases with increasing molar charge ratios.