Research Article

Cationic Polyene Phospholipids as DNA Carriers for Ocular Gene Therapy

Figure 6

EPC lipoplex cytotoxicity. ARPE-19 cell viability for EPC lipoplexes with either Chol or DOPE as colipids at various N/P molar charge ratios incubated up to 72 h. Horizontal line at 75% viability represents the threshold according to the ISO standard for in vitro testing of biological devices. C+ represents untreated cells and C− represents cells treated to induce cell death. Statistical significance ( ) of 95% ( ).
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