Lack of Association between TLR4 Genetic Polymorphisms and Diabetic Nephropathy in a Chinese Population
Table 1
Clinical characteristics of the study samples.
Cases
Controls
Samples ()
621
832
Male/female ()
348/274
352/480
Age (years)
62.42 ± 12.67
63.31 ± 10.56
BMI (years)
24.95 ± 3.86
24.00 ± 3.35
Age at diagnosis of diabetes (years)
53.56 ± 12.27
42.38 ± 10.22
Duration of diabetes (years)
9.00 (3.00, 14.00)
10.00 (7.00, 14.00)
Hemoglobin A1C (%)
9.34 ± 2.29
8.68 ± 2.10
Systolic blood pressure (mmHg)
140.04 ± 19.27
134.52 ± 18.27
Diastolic blood pressure (mmHg)
82.53 ± 9.90
79.57 ± 9.05
AERs (mg/24 H)
93.09 (47.47, 296.27)
9.23 (6.40, 14.58)
eGFR*
109.81 (81.62, 136.87)
121.57 (103.40, 144.84)
Data are , mean ± SD, or median (interquartile range). BMI: body mass index. AERs: albumin excretion rates. eGFR: estimated glomerular filtration rate. eGFR* was calculated by using a formula developed by the Modification of Diet in Renal Disease study group with adjustment for Chinese ethnicity.
