Lack of Association between TLR4 Genetic Polymorphisms and Diabetic Nephropathy in a Chinese Population

Table 2

Associations of TLR4 SNPs with type 2 diabetic nephropathy.

SNP	Chr. position (Build 37.3)	Major/minor allele	Risk allele	Cases		Controls		OR for minor allele (95% CI)	𝑃 value
				(𝑛=621)		(𝑛=832)
				Minor allele frequencies	Genotype count 11/12/22^#	Minor allele frequencies	Genotype count 11/12/22^#
rs10759932	9:120465144	T/C	T	0.310	290/236/65	0.309	392/336/83	1.001 (0.851–1.177)	0.993
rs1927911	9:120470054	C/T	T	0.435	201/289/121	0.427	267/403/148	1.030 (0.887–1.196)	0.698
rs11536879	9:120472211	A/G	G	0.125	471/129/12	0.120	630/169/13	1.047 (0.835–1.312)	0.691
rs1927907	9:120472764	G/A	A	0.272	320/218/51	0.260	449/294/62	1.064 (0.894–1.260)	0.477
rs11536889	9:120478131	G/C	G	0.221	371/224/25	0.216	511/275/41	1.031 (0.862–1.231)	0.741
rs7044464	9:120481397	T/A	A	0.093	503/110/2	0.084	694/127/6	1.113 (0.859–1.443)	0.417
rs7856729	9:120481856	G/T	T	0.093	506/111/2	0.086	691/131/6	1.084 (0.838–1.402)	0.541

#11, major allele homozygotes; 12, heterozygotes; 22, minor allele homozygotes.
The OR with 95% CI shown is for the minor allele.