Research Article
Lack of Association between TLR4 Genetic Polymorphisms and Diabetic Nephropathy in a Chinese Population
Table 2
Associations of TLR4 SNPs with type 2 diabetic nephropathy.
|
SNP |
Chr. position (Build 37.3) |
Major/minor allele |
Risk allele | Cases | Controls | OR for minor allele (95% CI) | value | () | () | Minor allele frequencies | Genotype count 11/12/22# | Minor allele frequencies | Genotype count 11/12/22# |
| rs10759932 | 9:120465144 | T/C | T | 0.310 | 290/236/65 | 0.309 | 392/336/83 | 1.001 (0.851–1.177) | 0.993 | rs1927911 | 9:120470054 | C/T | T | 0.435 | 201/289/121 | 0.427 | 267/403/148 | 1.030 (0.887–1.196) | 0.698 | rs11536879 | 9:120472211 | A/G | G | 0.125 | 471/129/12 | 0.120 | 630/169/13 | 1.047 (0.835–1.312) | 0.691 | rs1927907 | 9:120472764 | G/A | A | 0.272 | 320/218/51 | 0.260 | 449/294/62 | 1.064 (0.894–1.260) | 0.477 | rs11536889 | 9:120478131 | G/C | G | 0.221 | 371/224/25 | 0.216 | 511/275/41 | 1.031 (0.862–1.231) | 0.741 | rs7044464 | 9:120481397 | T/A | A | 0.093 | 503/110/2 | 0.084 | 694/127/6 | 1.113 (0.859–1.443) | 0.417 | rs7856729 | 9:120481856 | G/T | T | 0.093 | 506/111/2 | 0.086 | 691/131/6 | 1.084 (0.838–1.402) | 0.541 |
|
|
11, major allele homozygotes; 12, heterozygotes; 22, minor allele homozygotes. The OR with 95% CI shown is for the minor allele.
|