Antioxidant Defense Enzyme Genes and Asthma Susceptibility: Gender-Specific Effects and Heterogeneity in Gene-Gene Interactions between Pathogenetic Variants of the Disease
Figure 1
The results of statistical modeling of gene-gene interactions in allergic asthma using set association approach. Significance level of statistic as a function of the number of SNPs in different genes which are included at each step for gene-gene interactions analysis. The smallest significance level, , occurs with 5 SNPs in males and with 3 SNPs in females. The interacting genes in the models are circled in red.
