Investigations of Curcumin and Resveratrol on Neurite Outgrowth: Perspectives on Spinal Muscular Atrophy
Figure 2
Neurite outgrowth analysis of the SMN knockdown PC12 cells and compound treatments. (a) Comparison of the neurite lengths between wt and SMN knockdown PC12 cells at 3 and 7 days of differentiation, two-way ANOVA (), two group comparisons with Mann-Whitney -test (, ). (b) VPA (2 mM) was applied to both the wt and SMN knockdown cells for 3 days as a positive control, two-way ANOVA (), two group comparisons with Mann-Whitney -test (, ). Neurite lengths of the curcumin (500 nM) and resveratrol (5 μM) treated SMN knockdown cells at 3 days of differentiation, Kruskal-Wallis test. Data are presented as means ± SE, , n.s: non significant.