Research Article

Investigations of Curcumin and Resveratrol on Neurite Outgrowth: Perspectives on Spinal Muscular Atrophy

Figure 3

Effects of curcumin on SMN protein expression. (a) Representative images and quantification of the nuclear bodies of 3-day differentiated wt PC12 cells: SMN staining (green), DAPI staining (blue), and the merged images of untreated and curcumin treated cells. Arrows indicate the nuclear bodies. Scale bar; 10 μm. Mann-Whitney -test. (b) Western blot images and quantification of the total SMN protein level after 3 and 7 days of curcumin treatment in wt PC12 cells, two-way ANOVA ( ), two group comparisons with Mann-Whitney -test. Data are presented as means ± SE. (UT, untreated; CT, curcumin treated, n.s: non significant, ).
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