Potent Anti-Inflammatory Activity of Carbohydrate Polymer with Oxide of Zinc

Figure 1

Effects of Pebisut on inflammatory cytokine production induced by LPS. Peripheral blood mononuclear cells were purified and incubated in the presence of Pebisut (1 : 100 or 1 : 500) with or without LPS (100 ng/mL) stimulation during 18 hrs. After incubation, supernatants were collected to determinate cytokine concentration by CBA. (a) IL-6, (b) TNF, (c) IL-1β, (d) IL-8, and (e) nitrite. The data are expressed as the mean ± SEM and were analyzed with one-way ANOVA followed by Bonferroni’s comparison test (^∗∗∗𝑃<0.001, ^∗∗𝑃<0.01, and ^∗𝑃<0.05). Data are representative of three independent experiments.

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