A Derived Network-Based Interferon-Related Signature of Human Macrophages Responding to Mycobacterium tuberculosis
Figure 4
Illustration of TMtb-iNet in the context of the molecular network. (a) TMtb-iNet and its cognate hubs are laid out according to the information about subcellular localization as annotated in NCBI GO. Those nodes shown as circles are genes from TMtb-iNet and those nodes shown as triangles are hubs with direct interaction with gene products in TMtb-iNet. See the complete gene list in Table S2. (b) Illustration of the expression pattern of TMtb-iNet as well as its cognate hubs in THP-1 cells at 4 h, 18 h, and 48 h after M. tb infection. See also Table S3 for detailed expression levels.
