Research Article

A Derived Network-Based Interferon-Related Signature of Human Macrophages Responding to Mycobacterium tuberculosis

Table 5

GSEA using transcriptome data of PBMCs from AIDS mothers with infants.

Group comparison1THP1r2Mtb-inducedTMtb-iNetTMtb-iEx
NES2FDR3Correlation3NES2FDR3Correlation3NES2FDR3Correlation3

Non_Tr_HIV_M versus Neg_M2.93 0.000 Positive3.16 0.000 Positive1.98 0.000 Positive
Tr_HIV_M versus Neg_M2.20 0.000 Positive2.32 0.000 Positive1.44 0.011 Positive

1Non_Tr_HIV_M: HIV-1 positive mothers who did not transmit the virus to their infants; Tr_HIV_M: HIV-1 positive mothers who perinatally transmitted the virus to their infants; Neg_M: HIV negative mothers.
2,3The same as Table 1.