Adrenergic Activation of Melatonin Secretion in Ovine Pineal Explants in Short-Term Superfusion Culture Occurs via Protein Synthesis Independent and Dependent Phenomena
Figure 2
Experiment II. Time-course of NE-evoked changes in melatonin secretion from the ovine pineal explants. The ovine pineal glands () were divided into four explants, which were randomly assigned to the control and experimental groups. The explants were treated with NE as follows: group I, from 361 to 420 min and from 541 to 600 min of the experiment; group II, between 361 and 540 min of the experiment; and group III, between 361 and 720 min of the experiment. The explants from group IV (control) were not treated with NE. The mean melatonin secretion between 301 min and 360 min of the experiment was taken as 100%. The data presented are means. Red bars are periods of incubation in the medium with NE.
