Serum and Urinary NGAL in Septic Newborns

Table 3

Serum and urinary NGAL levels in septic newborns with and without urinary tract infections on the following time points. Mean value, 95% CI, and statistical significance of differences between the subgroups (𝑈 Mann-Whitney test) are presented, together with intragroup changes (ANOVA test).

	Urinary tract infection; (𝑁=17)	Septic patients without UTI; (𝑁=54)	𝑃
sNGAL (ng/dL)
Initial	188.6 (102.1–275.0)	246.4 (192.0–300.7)	NS
After 24 hours	250.5 (108.8–392.3)	232.5 (178.9–286.1)	NS
After 48 hours	170.3 (76.8–263.8)	164.1 (119.7–208.6)	NS
ANOVA	NS	𝑃<0.001
uNGAL (ng/dL)
Initial	250.5 (108.8–392.3)	158.2 (91.0–225.4)	0.001
After 24 hours	275.7 (150.5–401.0)	126.7 (68.6–184.7)	0.003
After 48 hours	189.8 (69.5–310.2)	108.3 (58.5–158.2)	NS
ANOVA	0.07	NS
uNGAL/sNGAL ratio
Initial	4.35 (0.53–8.18)	0.59 (0.34–0.85)	<0.001
After 24 hours	2.58 (0.98–3.77)	0.52 (0.38–0.67)	<0.001
After 48 hours	1.07 (0.66–1.49)	0.66 (0.44–0.88)	0.04
ANOVA	NS	NS