Review Article

Timing Embryo Segmentation: Dynamics and Regulatory Mechanisms of the Vertebrate Segmentation Clock

Table 1

Genes belonging to the signalling pathways Notch, Wnt, or Fgf shown to have an oscillatory behaviour in mouse, chick, and zebrafish embryos.

MouseChickZebrafish

Notchhes1 [54]hairy1 [32]deltaC [62]
hes5 [57]hairy2 [54]her1 [65]
hes7 [56]hey2 [55]her7 [66]
hey1 [64]lfng [59, 61]her2/4/15 [64]
hey2 [55]nup37 [64]nrarp [67]
lfng [60]nrarp [67]
nkd1 [68]
nrarp [63]

Wntaxin2 [35]axin2 [64]tbx16 [64]
dact1 [69]gpr177 [64]
dkk1 [64]T [64]
myc [64]
sp5 [64]
tnfrsf19 [64]

FgfBcl2/11 [64]dusp6/2 [64]tbx16 [64]
dusp4 [70]fgf3 [64]
dusp6 [63]Snail1 [64]
egr1 [64]snail2 [71]
shp2 [64]raf1 [64]
snail1 [71]
spry2 [63]
spry4 [72]