Stem Cell Niches in Glioblastoma: A Neuropathological View
Figure 1
(a) Infiltration area with many positive cells on vessels of different size, Nestin, DAB, 200x. (b) Transition area: medium size vessels with no cell around, GFAP, DAB, 100x. (c) Same area with many positive cells around vessels, Nestin, DAB, 100x. (d) Proliferation area: cuffing of tumor cells around vessels; GFAP+ cells are in an external position, DAB, 200x. (e) Id Nestin+ cells prevail and are located in the inner layer of the cuffing, DAB, 200x. (f) Hyperproliferating area with a circumscribed necrosis: most cells do not express GFAP, DAB, 100x. (g) The same area: the cells strongly express Nestin, DAB, 100x. (h) Id for GFAP, DAB, 400x, and (i) Nestin, DAB, 400x.
