Research Article

Antioxidant Potential, DNA Protection, and HPLC-DAD Analysis of Neglected Medicinal Jurinea dolomiaea Roots

Table 3

IC50 values of different antioxidant activities of extract and derived fractions of J. dolomiaea.

ActivityIC50 (μg/mL)
JDMEJDHEJDCEJDEEJDBEJDAEStandard

DPPH scavenging activity194.7 ± 1.3b219.7 ± 2.1c147.2 ± 1.4d41.1 ± 1.0f132.9 ± 2.1e305.2 ± 1.9a25.1 ± 0.8g
Hydrogen peroxide scavenging activity306.7 ± 2.1b409.6 ± 1.7a190.9 ± 1.6d42.2 ± 0.9g118.4 ± 1.1e231.9 ± 1.3c99.0 ± 1.1f
Hydroxyl radical scavenging activity133.0 ± 4.6d385.0 ± 7.4a159.2 ± 4.2c47.4 ± 3.3f77.0 ± 3.5e300.1 ± 5.5b10.2 ± 0.7g
ABTS scavenging activity93.3 ± 2.2e568.0 ± 4.1a191.6 ± 1.5c46.7 ± 0.6g112.5 ± 0.9d324.1 ± 2.1b55.0 ± 1.0f
Antilipid per oxidation activity172.4 ± 3.1d2075.0 ± 10.3a450.1 ± 3.3c54.3 ± 1.6f136.2 ± 1.4e482.5 ± 2.6b31.0 ± 0.6g
β-Carotene bleaching scavenging activity114.4 ± 0.8d254.0 ± 1.0b181.7 ± 2.0c82.8 ± 0.6e86.5 ± 1.1e267.4 ± 1.3a35.0 ± 1.8f
Superoxide radical scavenging activity215.1 ± 1.6c257.3 ± 2.1b91.7 ± 1.3e106.7 ± 2.5d83.8 ± 0.7f497.8 ± 4.2a41.0 ± 0.6g
NO radical scavenging activity237.3 ± 1.3d781.9 ± 4.3a92.0 ± 1.0f131.6 ± 1.4e388.2 ± 4.1b301.3 ± 3.2c40.9 ± 2.3g

Values are expressed as mean ± SD ( ); means with superscripts with different letters in the rows are significantly ( ) different from each other.