Research Article

Amarogentin, a Secoiridoid Glycoside, Abrogates Platelet Activation through PLCγ2-PKC and MAPK Pathways

Figure 5

Hypothesis regarding the inhibitory signaling of amarogentin in platelet activation. Amarogentin may inhibit both the PLCγ2-PKC-p47 cascades and MAPK signaling pathway, ultimately inhibiting platelet activation. DAG: diacylglycerol; IP3: inositol 1,4,5-trisphosphate.
728019.fig.005