Research Article

C-Kit Expression, Angiogenesis, and Grading in Canine Mast Cell Tumour: A Unique Model to Study C-Kit Driven Human Malignancies

Figure 1

(a) CMCT with a low MVD. Double staining is performed combining immunohistochemistry with toluidine blue histochemistry. Single arrows indicate blood vessels red-brown immunostained with primary anti-factor VIII-related antigen (FVIII-RA) at ×200 magnification. (b) CMCT with a high MVD. Double staining is performed combining immunohistochemistry toluidine blue histochemistry. Single arrows indicate clusters of blue stained neoplastic mast cells, while double arrows indicate blood vessels red-brown immunostained with a primary anti-FVIII-RA at ×200 magnification.
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(a)
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(b)