BioMed Research International / 2014 / Article / Tab 1 / Review Article
Mannose-Binding Lectin Codon 54 Gene Polymorphism and Vulvovaginal Candidiasis: A Systematic Review and Meta-Analysis Table 1 Characteristics of case-control studies which are included in meta-analysis.
First author, year of publication Country Ethnicity Participant origin Average agea of Sample size (cases/controls) No. of genotypes (cases/controls)Cases Controls AA AB BB Studies describing association between MBL codon 54 gene polymorphism and RVVC Babula, 2003 [14 ] Latvia Latvian Hospital outpatient service 27 (18–35) 25 (18–35) 42/43 13/39 26/4 3/0 Liu, 2006 [17 ] China Chinese Hospital outpatient service 29 ± 6 31 ± 5 6/54b 1/43 5/8 0 Giraldo, 2007 [16 ] Brazil White/nonwhite Hospital outpatient service 31 (18–68)c 33 (16–70) 50/66 31/53 13/12 6/1 Donders, 2008 [18 ] Belgium Caucasian, Asian Hospital outpatient service 36 ± 9 33 ± 10 109/55 69/48 36/7 4/0 Wojitani, 2012 [15 ] Brazil White/nonwhite Hospital outpatient service 32 (18–50) 30 (19–49) 100/100 58/84 30/15 12/1 Studies describing association between MBL codon 54 gene polymorphism and VVC Liu, 2006 [17 ] China Chinese Hospital outpatient service 33 ± 8 31 ± 5 51/54c 34/43 17/8 0 Giraldo, 2007 [16 ] Brazil White/nonwhite Hospital outpatient service 31 (18–68)c 33 (16–70) 28/66 18/53 10/12 0/1
MBL: mannose-lectin binding; RVVC: recurrent vulvovaginal candidiasis; VVC: vulvovaginal candidiasis.
a Expressed as median with range or mean ± standard deviation, as reported in the original paper.
b For three of 51 patients, genotypes were not determined because DNA could not be extracted from the respective samples.
c Calculated on the overall group of (R)VVC cases, as reported in the original paper.