Left-Sided Whole Breast Irradiation with Hybrid-IMRT and Helical Tomotherapy Dosimetric Comparison

Table 2

Plan evaluation parameters for hIMRT and lTomo plans.

Variable	hIMRT		lTomo		𝑃 value
	Range	Mean ± SD	Range	Mean ± SD
PTV
𝐷mean (Gy)	53.08–52.14	52.31 ± 0.09	52.27–51.25	51.68 ± 0.24	<0.001
𝐷max(Gy)	58.96–54.33	56.39 ± 1.29	58.49–53.10	54.97 ± 1.17	0.014
HI (%)	0.99–0.79	0.92 ± 0.04	1.00–0.97	0.99 ± 0.01	<0.001
CI	0.79–0.55	0.73 ± 0.04	0.82–0.64	0.75 ± 0.04	0.006
Left lung
𝐷mean (Gy)	16.38–6.15	10.03 ± 2.52	9.64–4.37	6.50 ± 1.39	<0.001
𝑉5 (%)	50.71–21.60	33.14 ± 7.31	40.22–16.63	24.74 ± 5.24	<0.001
𝑉10 (%)	39.64–14.64	23.54 ± 6.11	26.65–10.92	16.70 ± 4.07	<0.001
𝑉20 (%)	32.90–9.56	18.64 ± 5.61	17.44–2.50	10.70 ± 3.42	<0.001
Right lung
𝐷mean (Gy)	1.30–0.38	0.94 ± 0.25	1.54–0.27	0.51 ± 0.23	<0.001
Heart
𝐷mean (Gy)	11.12–1.77	6.08 ± 2.74	5.36–0.85	2.76 ± 1.21	<0.001
𝑉10 (%)	28.56–0.29	12.93 ± 8.02	13.00–0.00	5.14 ± 3.99	<0.001
𝑉25 (%)	19.32–0.15	8.04 ± 5.64	7.69–0.00	1.80 ± 1.76	<0.001
𝑉35 (%)	13.94–0.01	5.20 ± 4.11	3.64–0.00	0.82 ± 1.07	<0.001
Right breast
𝐷mean (Gy)	3.78–0.43	1.32 ± 0.78	3.23–0.38	1.33 ± 0.66	0.476
𝑉5 (%)	12.00–0.02	3.31 ± 3.78	13.98–0.01	5.70 ± 3.66	<0.001
𝑉10 (%)	7.50–0.00	1.72 ± 2.28	9.77–0.03	2.99 ± 2.44	0.003