Reexpression of Let-7g MicroRNA Inhibits the Proliferation and Migration via K-Ras/HMGA2/Snail Axis in Hepatocellular Carcinoma
Figure 4
Reexpression of let-7g inhibited the migration of MHCC97-H and HCCLM3 cells. (a) Qualification of wound-healing assay of MHCC97-H after re-expression of let-7g for 0 and 48 hours. (b) Qualification of wound-healing assay of HCCLM-3 after re-expression of let-7g for 0 and 48 hours. (c) Quantitation of wound-healing assay of MHCC97-H. Migration of MHCC97-H cells was significantly retarded in comparison with scramble sequence control group. There is strikingly significant difference between group transfected with scramble sequence and group transfected with let-7g group (**, one-way ANOVA analysis). (d) Quantitation of wound-healing assay of HCCLM-3. Highly similarly, migration of HCCLM-3 cells was also significantly suppressed compared with scramble sequence group. (**, one-way ANOVA analysis). The mean and standard error from triplicate experiments are indicated.
