Combinatorial Control of Transgene Expression by Hypoxia-Responsive Promoter and MicroRNA Regulation for Neural Stem Cell-Based Cancer Therapy
Figure 1
iPS cell line characterization and neural differentiation in vitro. (a) iPS cell line characterization. From left to right: iPS cell colony, AP staining, immunostaining to show protein expression of embryonic stem cell markers SSEA-3, SSEA-4, TRA-1-60, and TRA-1-81. (b) Neural differentiation in vitro. From left to right: immunostaining to show protein expression of NSC early stage marker nestin, NSC differentiation markers GFAP (glial cell marker), and β-III tubulin (neuron marker).
