Research Article

Combinatorial Control of Transgene Expression by Hypoxia-Responsive Promoter and MicroRNA Regulation for Neural Stem Cell-Based Cancer Therapy

Table 1

MicroRNA targeting (mirT) sequences.

mirTSequence

miR-199a-5pS1 -CTAGATAAgaacaggtagtctgaacactgggCGATgaacaggtagtctgaacactggg-
S2 -ACGCGTgaacaggtagtctgaacactgggTCACgaacaggtagtctgaacactgggGCATG-
AS1 -ACGCGTcccagtgttcagactacctgttcATCGcccagtgttcagactacctgttcTTAT-
AS2 -CcccagtgttcagactacctgttcGTGAcccagtgttcagactacctgttc-

ScrTS1 -CTAGAtaatttatgatctgcgcgtggagacgcccgattttatgatctgcgcgtggagacgcc-
S2 -acgcgttttatgatctgcgcgtggagacgcctcactttatgatctgcgcgtggagacgccGCATG-
AS1 -acgcgtggcgtctccacgcgcagatcataaaatcgggcgtctccacgcgcagatcataaattaT-
AS2 -Cggcgtctccacgcgcagatcataaagtgaggcgtctccacgcgcagatcataaa-