Integration of Residue Attributes for Sequence Diversity Characterization of Terpenoid Enzymes
Figure 6
Principal component analysis of terpenoid synthases. Left: principal component analysis of the terpenoid synthase subfamilies where amino acid residues are encoded in 8-bit binary method. PC1 and PC2 show a combined variance of 14.84 percent explained variance. Right: principal component analysis of the same data set encoded using the biochemical and physical properties of amino acid residues. PC1 and PC2 in this case explain 30.02 percent variance. The four subfamilies clustered are monoterpenoid, diterpenoid, triterpenoid, and sesquiterpenoid synthases. Triterpenoid synthases and subgroups of terpenoid synthases are distinctly different in structure compared to the other synthases.
