Review Article

Estrogen Deficiency and the Origin of Obesity during Menopause

Figure 2

Estrogen hypothalamic control of obesity. ER alpha in the brain regulates body weight in both males and females ▸ ER alpha in female SF1 neurons regulates energy expenditure and fat distribution ▸ ER alpha in female POMC neurons regulates food intake. POMC: proopiomelanocortin; SF1: steroidogenic factor-1.
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