Estrogen Deficiency and the Origin of Obesity during Menopause
Figure 2
Estrogen hypothalamic control of obesity. ER alpha in the brain regulates body weight in both males and females ▸ ER alpha in female SF1 neurons regulates energy expenditure and fat distribution ▸ ER alpha in female POMC neurons regulates food intake. POMC: proopiomelanocortin; SF1: steroidogenic factor-1.