In Vitro Screening for β-Hydroxy-β-methylglutaryl-CoA Reductase Inhibitory and Antioxidant Activity of Sequentially Extracted Fractions of Ficus palmata Forsk

Table 2

IC₅₀ value of different extracts of FPL and FPB against HMG-CoA reductase enzyme activity.

Plant extracts	IC50 value (µg/mL)
FPLH	38±2.15^∗
FPLD	58±3.15^∗
FPLE	27±1.15^∗∗
FPLM	65±3.24^∗
FPLA	NS
FPBH	NS
FPBD	30±1.44^∗∗
FPBE	35±1.64^∗
FPBM	45±2.45^∗
FPBA	9.1±0.53^∗∗
Pravastatin	70.25** nM

The values are expressed as mean ± SD (𝑛=3). Nonsignificant (NS), significantly different ^∗𝑃<0.005, and ^∗∗𝑃<0.001 versus without inhibitor.