Colorectal Cancer: Prevention and Management of Metastatic Disease
Table 2
Patients with primary colorectal cancer identified to be at high risk for local-regional recurrence and/or peritoneal metastases. Groups 1–10 are candidates for prophylactic HIPEC or EPIC as part of the primary colorectal cancer resection. Groups 1–4 are candidates for proactive second-look surgery.
(1) Visible evidence of peritoneal metastases
(2) Ovarian cysts showing adenocarcinoma suggested to be of gastrointestinal origin
(3) Perforated cancer
(4) Positive margins of excision
(5) Positive cytology either before or after cancer resection
(6) Adjacent organ involvement of cancer-induced fistula
(7) T3 mucinous cancer
(8) T4 cancer or positive “imprint cytology” of the primary cancer
