Rosiglitazone Regulates Anti-Inflammation and Growth Inhibition via PTEN

Figure 6

Effects of rosiglitazone on ROS generation in shLuc and shPTEN cells. Cells were treated with 25 𝜇M rosiglitazone prior to stimulation with 5 𝜇g/mL LPS for 3 h. Cell were harvested, stained with DCFH-DA, and then analyzed by FACScan. Data shown are representative of three individual experiments. Data are expressed as mean ± SEM obtained from three individual cultures. MFI stands for mean fluorescence intensity. ^∗∗𝑃 < 0.01 compared with the control, untreated shLuc cells.