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| Number | Title | Target sample size | Study type | Country |
|
| 1 | Continuous Positive Airway Pressure (CPAP) in Patients with Impaired Vision due to Diabetic Retinopathy and Concurrent Obstructive Sleep Apnoea (OSA): ROSA trial | 150 | Interventional | UK |
|
| 2 | Screening intervals for diabetic retinopathy | 24,000 | Observational | UK |
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| 3 | Computer Detection of Diabetic Retinopathy Compared to Clinical Examination | 600 | Observational | USA |
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| 4 | Computer-based Screening for Diabetic Retinopathy | 10,000 | Observational | USA |
|
| 5 | Prompt Panretinal Photocoagulation Versus Ranibizumab + Deferred Panretinal Photocoagulation for Proliferative Diabetic Retinopathy | 316 | Interventional | USA |
|
| 6 | Treatment for CI-DME in Eyes With Very Good VA Stud | 702 | Interventional | USA |
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| 7 | The Role of Prostaglandins in the Progression of Diabetic Retinopathy | 100 | Interventional | USA |
|
| 8 | Comparison of Phase-variance Optical Coherence Tomography and Fluorescein Angiography in Retinovascular Imaging | 78 | Observational | USA |
|
| 9 | The Use of Alpha Lipoic Acid for the Treatment and Prevention of Diabetic Retinopathy | 200 | Interventional | USA |
|
| 10 | NSAID Phase II for Non-central Involved Diabetic Macular Edema (DME) | 120 | Interventional | USA |
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| 11 | Rapid, Non-invasive, Regional Functional Imaging of the Retina. (Diabetic Retinopathy Diagnosis Device) | 315 | Observational | USA |
|
| 12 | A Safety and Efficacy Study of Vitreosolve for Non-Proliferative Diabetic Retinopathy Subjects | 160 | Interventional | India |
|
| 13 | Intravitreal Bevacizumab for Retinal Disorders | 150 | Interventional | India |
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| 14 | A study to Find out Whether Vitrectomy Is Better Than Laser for Diabetic Patients with Partial Bleeding into the Vitreous Jelly | 64 | Interventional | India |
|
| 15 | Anterior and Posterior Segment Vascular Changes Following Laser and Anti-Vascular Endothelial Growth Factor (VEGF) Treatment of Diabetic Retinopathy | 64 | Interventional | Canada |
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| 16 | Prospective Study Phase: Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye | 381 | Observational | Canada |
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| 17 | A Comparison of Islet Cell Transplantation With Medical Therapy for the Treatment of Diabetic Eye Disease | 40 | Interventional | Canada |
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| 18 | Prospective Study Phase: Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye | 381 | Observational | Canada |
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| 19 | Safety and Efficacy of Low-Fluence PRP for PDR | 60 | Interventional | Mexico |
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| 20 | Topic Antiinflammatory Therapy Added to Selective Photocoagulation in Macular Edema | 84 | Interventional | Mexico |
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| 21 | Standard versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy | 5,000 | Interventional | Japan |
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| 22 | Japan Public Health Center-based Prospective Study-NEXT on Glaucoma, Age-Related Macular Degeneration and Diabetic Retinopathy | 4,000 | Observational | Japan |
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| 23 | Research on Age-Related Macular Degeneration and Diabetic Complications Using Non-invasive AGEs Measurement Equipment | 500 | Observational | Japan |
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| 24 | Choroidal Structure of Diabetic Retinopathy Eye on OCT Image After the Treatment | 50 | Interventional | Japan |
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| 25 | Diabetes-Related Eye Disease Study | 400 | Observational | Japan |
|
| 26 | The Effect of NSAID for the Cystoid Macular Edema After Panretinal Photocoagulation in Diabetic Retinopathy | 140 | Interventional | Japan |
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| 27 | To Investigate the Effects of Panretinal Photocoagulation by a Multicolor laser Photocoagulator with a Scan Delivery System in Eyes with Proliferative Diabetic Retinopathy | 60 | Interventional | Japan |
|
| 28 | A Pilot Study on the Effects of ILARIS on Patients With Proliferative Diabetic Retinopathy (PDRP) | 10 | Interventional | Switzerland |
|
| 29 | Panretinal Photocoagulation for Diabetic Retinopathy With PASCAL Laser | 60 | Interventional | Brazil |
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| 30 | Bevacizumab as Adjunctive Treatment to Laser Panretinal Photocoagulation for Proliferative Diabetic Retinopathy | 30 | Interventional | Brazil |
|
| 31 | Thiazolidinedione (TZD) on the Diabetic Retinopathy and Nephropathy | 200 | Interventional | Taiwan |
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| 32 | Genetic Association of Diabetic Retinopathy-1 | 200 | Observational | Taiwan |
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| 33 | Retinal Adaptation to Intensified Insulin Therapy and Bariatric Surgery in Patients With Diabetes | 100 | Observational | Denmark |
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| 34 | Topical Application of Latanoprost in Diabetic Retinopathy | 50 | Interventional | Denmark |
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| 35 | A Phase 2 Clinical Study to Investigate Effects of Darapladib in Subjects With Diabetic Macular Edema | 54 | Interventional | Australia |
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| 36 | Trial of Switching Between Intravitreal Bevacizumab (Avastin) & Intravitreal Dexamethasone (Ozurdex) for Persistent Diabetic Macular Oedema | 50 | Interventional | Australia |
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| 37 | Intravitreal Triamcinolone Acetonide for Diabetic Macular Edema | 60 | Interventional | Germany |
|
| 38 | Multicenter 12 Months Clinical Study to Evaluate Efficacy and Safety of Ranibizumab Alone or in Combination With Laser Photocoagulation vs. Laser Photocoagulation Alone in Proliferative Diabetic Retinopathy (PRIDE) | 120 | Interventional | Germany |
|
| 39 | Effects of Fenofibrate on Endothelial Progenitor Cells in Type 1 Diabetes | 38 | Interventional | Italy |
|
| 40 | Effect of Folic Acid, Vitamin B6 and Vitamin B12 in Diabetic Retinopathy | 160 | Interventional | Italy |
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| 41 | Intravitreal Ozurdex After Pars Plana Vitrectomy for Proliferative Diabetic Retinopathy | 100 | Interventional | Sweden |
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| 42 | Vitreous Analysis in Proliferative Diabetic Retinopathy | 200 | Observational | Sweden |
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| 43 | Different Interventions Promoting Diabetic Retinopathy Screening Among Chinese Type 2 diabetes: A Randomized Trial | 300 | Interventional | China |
|
| 44 | Clinical Investigation on Early Lesions in Diabetic Retinopathy | 500 | Observational | China |
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| 45 | Laser Photocoagulation in Patients with Diabetic Retinopathy Derived from New International Clinical Classification | 180 | Observational | China |
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| 46 | Effect of Berberine on Diabetic Retinopathy | 100 | Interventional | China |
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| 47 | Study of Evaluation on the Clinical Efficacy of Tradition Chinese Medicine in the Treatment of Non-Proliferative Diabetic Retinopathy | 60 | Interventional | China |
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| 48 | Clinical Study of Treatment with Kudiezi Injection in Nonproliferative Diabetic Retinopathy Patients | 80 | Interventional | China |
|
| 49 | Hemodynamics of Ocular Artery in Ischemic Ocular Diseases with TCD Study | 180 | Diagnostic test | China |
|
| 50 | Morphological and Functional Retinal Changes Following Retinal Photocoagulation | 50 | Interventional | Austria |
|
| 51 | Study Investigating the Levels and Effects of Low-grade Inflammation in Diabetic Retinopathy of Type 1 Diabetes | 50 | Observational | Austria |
|
| 52 | Choroidal Blood Flow Changes During Dark/Light Transitions in Patients With Insulin-Dependent Diabetes Mellitus (IDDM) | 80 | Interventional | Austria |
|
| 53 | Autologous Plasmin and Fibrinolytic System in Diabetic Retinopathy | 40 | Interventional | Korea, Republic of Korea |
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| 54 | Incidence of Macular Edema After Panretinal Photocoagulation (PRPC) Performed in a Single Session Versus Four Sessions in Diabetic Patients. | 90 | Interventional | France |
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| 55 | Trial of Yellow 577 nm Laser Versus Green 532 nm Laser for Proliferative Diabetic Retinopathy | 120 | Interventional | Malaysia |
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| 56 | Preoperative Injection of Bevacizumab Prior to Vitreoretinal Surgery in Diabetic Tractional Retinal Detachment | 50 | Interventional | Iran, Republic of Iran |
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| 57 | Effect of Intravitreal Bevacizumab on Early Post-Vitrectomy Hemorrhage in Diabetic Patients | 80 | Interventional | Iran, Republic of Iran |
|
| 58 | Intravitreal Adalimumab in Refractory Diabetic Retinopathy, Choroidal Neovascularization or Uveitis: A Pilot Study | 15 | Interventional | Lebanon |
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