Evidence for the Use of Isoflurane as a Replacement for Chloral Hydrate Anesthesia in Experimental Stroke: An Ethical Issue

Figure 2

Effects of chloral hydrate and isoflurane on 24 h survival and ischemic events rates after MCAO. Frequency of infarct patterns, subcortical infarct areas and total infarct areas (ischemic), nonischemic and dead animals related to anesthesia type: (a) chloral hydrate; (b) isoflurane. 𝑁=45 animals per group. Only ischemic animals were kept in the study.

(a)

(b)