Early Response Roles for Prolactin Cortisol and Circulating and Cellular Levels of Heat Shock Proteins 72 and 90α in Severe Sepsis and SIRS

Table 1

Demographic characteristics and severity scores by group (healthy subjects , SIRS , severe sepsis )**.

	Healthy subjects	SIRS	Severe sepsis	value*
Age (years)	47.3 ± 9.7	42.5 ± 13.0	54.7 ± 14.5^ab	0.003
Gender (male/female)	10 M/6 F	24 M/5 F	17 M/12 F	0.118
APACHE II		15.0 ± 5.4	22.0 ± 9.7^b	0.007
SOFA		8.0 ± 3.0	11.0 ± 4.0^b	0.006
SAPS III		50.0 ± 10.0	68.0 ± 14.0^b	0.0001

APACHE: acute physiology and chronic evaluation; SOFA: sequential organ failure assessment; SAPS III: simplified acute physiology score; SIRS: systematic inflammatory response syndrome, between healthy subjects and severe sepsis groups, and between SIRS and severe sepsis group.
*The value was calculated using the Kruskal-Wallis test and a value <0.05 was considered statistically significant.
**Data are expressed as means ± SD (standard deviation).