Borderline Ovarian Tumors and Diagnostic Dilemma of Intraoperative Diagnosis: Could Preoperative He4 Assay and ROMA Score Assessment Increase the Frozen Section Accuracy? A Multicenter Case-Control Study

Table 3

Preoperative serum value of CA125 and He4 biomarkers: absolute value and risk estimation according to predefined cut-off (in relation to hormonal status for He4) (only for CA125: Group_A versus Group_B).

		Number	Mean value	Standard deviation	value
Preoperative CA125 serum value (UI/L)	Group_A	43	52.92	83.26	n.s
	Group_B	70	56.32	71.85
Preoperative He4 serum value (pmol/L)	Group_A	43	89.99	175.07	—
	Group_B	—	—	—
			Category	Number (%)	value
CA125 cut-off value	Group_A	43	Over	15 (34.9)	n.s
			Under	28 (65.1)
	Group_B	70	Over	37 (52.9)
			Under	33 (47.1)
He4 cut-off value	Group_A	43	Over	24 (55.8)	—
			Under	19 (44.2)
	—	—	—	—
			—	—
ROMA score cut-off value	Group_A	43	Over	13 (30.2)	—
			Under	30 (69.8)
	—	—	—	—
			—	—