EXIA2: Web Server of Accurate and Rapid Protein Catalytic Residue Prediction

Figure 3

ROC curves for L55-Bound and L55-Unbound enzyme structures. Comparison of performance on 55 enzymes in their substrate-bounded (L55-Bound) form and substrate-unbounded form (L55-Unbound). The performances of L55-Unbound are similar to those of L55-Bound using only structure features (dashed lines) or using both structure features and sequence conservation (solid lines). The AUCROC for L55-Bound and L55-Unbound are 0.968 and 0.967, respectively, when both structure features and sequence conservation are used. The AUCROC are 0.950 and 0.947 for L55-Bound and L55-Unbound, respectively, when only structure features are used.