We Are Ageing

Table 1

Some of the most frequent studied genes concerning human longevity.

Gene	References
CETP	Barzilai et al. 2003	[32]
	Atzmon et al. 2005	[94]
	Cellini et al. 2005	[34]
	Novelli et al. 2008	[95]
	Sanders et al. 2010	[96]
	Soerensen et al. 2013	[33]
	Kolovou et al. 2014	[31]
	Sun et al. 2013	[97]
IGF pathway	Bonafè M et al. 2003	[98]
	Suh et al. 2008	[45]
	Albani et al. 2011	[99]
	Soerensen et al. 2012	[100]
FOXO family	Bonafè et al. 2003	[98]
	Willcox et al. 2008	[44]
	Soerensen et al. 2010	[101]
	Zeng et al. 2010	[102]
	Kleindorp et al. 2011	[103]
ACE	Schachter et al. 1994	[87]
	Faure-Delanef et al. 1998	[104]
	Panza et al. 2003	[105]
	Forero et al. 2006	[106]
	Nacmias et al. 2007	[107]
	Blanchè et al. 2001	[90]
	Petranović et al. 2012	[108]
	Fiuza-Luces et al. 2011	[109]
	Kolovou et al. 2014	[31]
SIRT1	Flachsbart et al. 2006	[110]
	Kuningas et al. 2007	[111]
	Kim et al. 2012	[112]
	Huang et al. 2013	[113]
Klotho	Arking et al. 2002	[114]
	Arking et al. 2005	[115]
	Invidia et al. 2010	[116]
hTERT	Atzmon et al. 2005	[94]
	Atzmon et al. 2010	[93]
APOE	Kervinen et al. 1994	[48]
	Schachter et al. 1994	[87]
	Blanché et al. 2001	[90]
	Wang et al. 2001	[117]
	Panza et al. 2003	[105]
	Feng et al. 2011	[118]
	Nebel et al. 2011	[119]
	Sebastiani et al. 2012	[120]
	Soerensen et al. 2013	[33]
	Schupf et al. 2013	[121]
	Beekman et al. 2013	[122]

IGF-1R: insulin-like growth factor 1 receptor, CETP: cholesteryl ester transfer protein, FOXO: forkhead box transcription, SIRT 1: sirtuin 1, hTERT: human telomerase reverse transcriptase, Apo: apolipoprotein, ACE: angiotensin-converting enzyme.