Oncogenic PIK3CA Mutation and Dysregulation in Human Salivary Duct Carcinoma

Table 1

Clinical and pathologic features of salivary duct carcinoma cases.

Case	Gender	Age	Location	Tumor size	Perineural invasion	Margin	Lymph node	Pleomorphic adenoma	HER2; expression	PIK3CA mutation
SDC1	M	60	Parotid	2.3 cm	+	−	1/2	−	+	−
SDC2	M	65	Parotid	2.2 cm	+	+	15/29	−	−	H1047R
SDC3	F	50	Parotid	1.7 cm	+	−	8/44	+	N/A	E545K
SDC4	M	58	Parotid	2.0 cm	+	− (close)	14/45	+	++	−
SDC5	M	67	Parotid	N/A	N/A	+	0/12	+	−	−
SDC6	M	71	Parotid	1.6 cm	+	− (close)	N/A	−	+++	−

Abbreviations: N/A: not available or not applicable; close: less than 0.1 cm.