Research Article

TET2 Overexpression in Chronic Lymphocytic Leukemia Is Unrelated to the Presence of TET2 Variations

Table 1

Characteristics of the 48 CLL patients included in the study.

ParameterCategory%

Age (years), 
median (range)
65 (37–84)
GenderMale54
White blood cells (×109/L), 
median (range)
24,980 
(10,130–96,510)
Lymphocytes (×109/L), 
median (range)
21,070 
(5,900–86,320)
Hemoglobin (×109/L), 
median (range)
13.6 
(11.5–15.8)
Platelet (×109/L), 
median (range)
176,500 
(70,000–333,000)
Binet stageA67
B27
C6
Lactate 
dehydrogenase
High7
2 microglobulinHigh25
IGHV Unmutated45
FISH abnormality*13q deletion56
11q deletion15
17p deletion2
Trisomy 1217
No FISH 
abnormalities
29

Some patients have more than one cytogenetic aberration.