Research Article
TET2 Overexpression in Chronic Lymphocytic Leukemia Is Unrelated to the Presence of TET2 Variations
Table 3
Known variations of TET2 detected in 26 CLL cases by next-generation sequencing.
| | SNP | rs | Region | Protein | (%) |
| | 86C>G | rs12498609 | exon 3 | Pro29Arg | 3 () | | 100C>T | rs111948941 | exon 3 | Leu34Phe | 2 () | | 521C>A | rs146031219 | exon 3 | Pro174His | 1 () | | 652G>A | rs6843141 | exon 3 | Val218Met | 2 () | | 1088C>T | rs17253672 | exon 3 | Pro363Leu | 2 () | | 1105C>T | rs150072691 | exon 3 | Arg369Trp | 1 () | | 2599T>C | rs144386291 | exon 3 | Tyr867His | 1 () | | 5162T>G | rs34402524 | exon 11 | Leu1721Trp | 4 () | | 5167C>T | rs146348065 | exon 11 | Pro1723Ser | 1 () | | 5284A>G | rs2454206 | exon 11 | Ile1762Val | 14 () | | 5333A>G | rs62621450 | exon 11 | His1778Arg | 3 () |
| | 3803 + 45G>A | rs17319679 | Intron 7 | — | 2 () | | 4045 − 35C>A | rs59519484 | Intron 8 | — | 1 () | |
*74G>A | rs60786079 | 3UTR | — | 3 () |
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N = nucleotide N 3 of the translation stop codon.
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