Clinical Outcomes and Prognostic Factors of 695 Nasopharyngeal Carcinoma Patients Treated with Intensity-Modulated Radiotherapy

Table 6

Univariate prognostic analysis.

Prognostic factors	LC		DFS		DSS		OS
	%		%		%		%
Gender
Male	89.6	0.176	74.6	0.133	83.7	0.096	76.2	0.041
Female	91.0		72.1		81.1		78.7
Age (years)
≦45	92.4	0.853	75.5	0.737	84.4	0.589	78.8	0.745
>45	87.1		72.5		81.8		75.4
T
T1/2	91.5	0.887	85.7	<0.000	92.8	<0.001	83.0	0.012
T3/4	88.9		66.8		77.2		73.5
N
N0/1	93.5	0.718	80.6	0.004	90.5	<0.001	82.3	0.021
N2/3	88.6		70.5		78.3		73.7
Clinical stage
I + II	93.5	0.123	79.5	0.036	91.5	0.008	89.5	<0.001
III + IV	88.0		71.2		78.8		70.7
Radiotherapy interruption
≦10 d	92.6	0.000	75.6	0.000	84.9	0.000	79.4	0.000
>10 d	76.3		64.1		71.8		62.8
HGB (g/L)
≦110	77.0	0.000	63.3	0.000	73.3	<0.001	70.0	<0.001
>110	91.4		75.3		84.3		78.0
Percentage of weight loss
≦10%	90.9	0.092	75.6	0.525	86.5	0.153	80.5	0.011
>10%	85.6		72.4		79.6		73.5
Chemotherapy or not given
IMRT	88.9	0.385	72.2	0.204	81.8	0.087	72.7	0.043
Chemo. + IMRT	90.4		75.0		83.9		79.4

HGB: hemoglobin; LC: local-regional control rates; DFS: disease-free survival; DSS: disease specific survival; OS: overall survival rate.