Clinical Study
Clinical Outcomes and Prognostic Factors of 695 Nasopharyngeal Carcinoma Patients Treated with Intensity-Modulated Radiotherapy
Table 6
Univariate prognostic analysis.
| Prognostic factors | LC | DFS | DSS | OS | % | | % | | % | | % | |
| Gender | | | | | | | | | Male | 89.6 | 0.176 | 74.6 | 0.133 | 83.7 | 0.096 | 76.2 | 0.041 | Female | 91.0 | 72.1 | 81.1 | 78.7 | Age (years) | | | | | | | | | ≦45 | 92.4 | 0.853 | 75.5 | 0.737 | 84.4 | 0.589 | 78.8 | 0.745 | >45 | 87.1 | 72.5 | 81.8 | 75.4 | T | | | | | | | | | T1/2 | 91.5 | 0.887 | 85.7 | <0.000 | 92.8 | <0.001 | 83.0 | 0.012 | T3/4 | 88.9 | 66.8 | 77.2 | 73.5 | N | | | | | | | | | N0/1 | 93.5 | 0.718 | 80.6 | 0.004 | 90.5 | <0.001 | 82.3 | 0.021 | N2/3 | 88.6 | 70.5 | 78.3 | 73.7 | Clinical stage | | | | | | | | | I + II | 93.5 | 0.123 | 79.5 | 0.036 | 91.5 | 0.008 | 89.5 | <0.001 | III + IV | 88.0 | 71.2 | 78.8 | 70.7 | Radiotherapy interruption | | | | | | | | | ≦10 d | 92.6 | 0.000 | 75.6 | 0.000 | 84.9 | 0.000 | 79.4 | 0.000 | >10 d | 76.3 | 64.1 | 71.8 | 62.8 | HGB (g/L) | | | | | | | | | ≦110 | 77.0 | 0.000 | 63.3 | 0.000 | 73.3 | <0.001 | 70.0 | <0.001 | >110 | 91.4 | 75.3 | 84.3 | 78.0 | Percentage of weight loss | | | | | | | | | ≦10% | 90.9 | 0.092 | 75.6 | 0.525 | 86.5 | 0.153 | 80.5 | 0.011 | >10% | 85.6 | 72.4 | 79.6 | 73.5 | Chemotherapy or not given | | | | | | | | | IMRT | 88.9 | 0.385 | 72.2 | 0.204 | 81.8 | 0.087 | 72.7 | 0.043 | Chemo. + IMRT | 90.4 | 75.0 | 83.9 | 79.4 |
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HGB: hemoglobin; LC: local-regional control rates; DFS: disease-free survival; DSS: disease specific survival; OS: overall survival rate.
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