Research Article

Niosomes of Ascorbic Acid and α-Tocopherol in the Cerebral Ischemia-Reperfusion Model in Male Rats

Table 3

Mean volume diameter of ascorbic acid loaded niosomes prepared by film hydration method after 48 h and remote loading method at different time intervals after preparation and storage at 4°C (mean ± SD, ).

Niosomal formulationsFilm hydration 
(m) ± SD
Remote loading 
(m) ± SD
48 h48 h1 month 2 months6 months

ST40/Chol 35 : 35 : 30
ST40/Chol 30 : 30 : 40
ST40/Chol 25 : 25 : 50
ST60/Chol 35 : 35 : 30
ST60/Chol 30 : 30 : 40
ST60/Chol 25 : 25 : 50